A simple and foolproof Mississippi pot roast made in a crockpot with just four pantry staple ingredients, delivering tender, flavorful meat with a tangy, rich sauce.
Do not open the crockpot lid frequently to avoid heat loss. Use fresh pepperoncini juice for best flavor. Butter is optional and can be substituted with plant-based alternatives for dairy-free. To thicken sauce, stir in a cornstarch slurry and cook on high for 15-20 minutes. Variations include adding vegetables, spicy pepperoncini, or using an Instant Pot for faster cooking.
Keywords: Mississippi pot roast, crockpot recipe, slow cooker roast, easy pot roast, ranch seasoning, au jus gravy, pepperoncini peppers, beginner recipe, comfort food